To mitigate warehousing and spoilage costs in emergency supply stockpiling, governments often partner with private companies to distribute emergency supplies across various locations in the commercial supply chain for regular demand rotation. Commonly, a “red line” is assigned to each location, with inventory below this line reserved solely for emergencies. This study introduces an Integrated Virtual Stockpile Pooling and On-Event Retrieval (VSPR) strategy that refines VSP by incorporating emergency retrieval costs into its design. We present a novel ranking method to solve VSPR’s three-stage optimization process, leading to a collaborative base-stock system, a priority-based red-line reassignment, and a greedy algorithm for efficient supply retrieval. We show that VSPR strategically reserves supplies at “key locations”, optimizing cost and response efficiency. A case study demonstrates that, compared with VSP, VSPR has the potential to reduce operational costs by up to 13.8% while enhancing service levels by up to 4.9%.